Detailed information

Gene

Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.

Buffer Formulation

PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Alternative Names

Kinurenic acid; Kynuronic acid; Kuinurenic acid; Transtorine

Application

Immunogen; SDS-PAGE; WB

Organism species

Pan-species (General)

Source

Protein conjugation

Traits

Freeze-dried powder

Expression System

Protein Conjugation

Item Name

Kynurenic Acid

Predicted Molecular Mass(KD)

189.2g/mol

Tag

No tag

Purity

>95%

OVA Conjugated Kynurenic Acid (KYNA)

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